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Foradil Certihaler

Merck & Co., Inc.

Drug Names(s): Formoterol fumarate multi-dose dry powder inhaler

Description: Foradil Certihaler is a multi-dose dry powder inhaler version of the long-acting bronchodilator formoterol.

Deal Structure: In November 1998, the SkyePharma and Novartis agreed to jointly develop a new formulation of Novartis' Foradil asthma drug using the SkyePharma's multi-dose dry powder inhaler. SkyePharma is responsible for producing the drug in its finished form, including supplying both the powder and the device as a product to Novartis. Under the arrangement, Novartis has paid SkyePharma technology access fee of 0.4 million and made an equity investment in SkyePharma amounting to 6.1 million. Novartis has also agreed to pay SkyePharma royalty income on future worldwide sales of the drug. In return, SkyePharma has granted Novartis an exclusive worldwide license to market Foradil in the new delivery form.

In the US, the Foradil franchise has been licensed by Novartis to Schering-Plough (Nov 2002).

In March 2009, Merck & Co and Schering-Plough announced that their Boards of Directors have unanimously approved a definitive merger agreement under which Merck and Schering-Plough will combine,...See full deal structure in Biomedtracker

Partners: Vectura Group Astellas Pharma, Inc.

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