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Roche Holding AG
Drug Names(s): Ro27-2441
Description: R411 is an oral dual alpha4beta1-alpha4beta7 integrin antagonist. These integrins are receptors that promote migration, activation, and increasedsurvival of inflammatory cells in the lung. They are found particular on Th2 lymphocytes, eosinophils and mast cells.
Pink Sheet US FDA, Advisory Committees Rarely Disagree
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