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1018 ISS

Dynavax Technologies Corporation

Drug Names(s): ISS-1018

Description: Dynavax Technologies is developing short, immunostimulatory DNA sequences (ISS). 1018 ISS is a CpG oligodeoxynucleotides (CpG-ODNs). CpG-ODNs affect innate and adaptive immune responses, including antigen presentation, costimulatory molecule expression, dendritic cell maturation, and induction of cytokines enhancing antibody-dependent cell-mediated cytotoxicity (ADCC).

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