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856464

GlaxoSmithKline plc

Drug Names(s): GSK856464

Description: 856464 is a melanin concentrating hormone (MCH) antagonist. MCH, a cyclic peptide, was first identified in teleost fish, where it appears to regulate color change. MCH neurons are almost exclusively expressed in the lateral hypothalamus and project to brain areas involved in feeding, reward and mood regulation.


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