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PINTA 745

Atara Biotherapeutics, Inc.

Drug Names(s): AMG 745

Description: PINTA 745 is a novel myostatin inhibiting peptibody. A peptibody is a protein construct made of a synthetic peptide that is fused to an antibody.

In preclinical studies, PINTA 745 was able to reduce inflammation and build muscle in models of chronic kidney disease.

Deal Structure: PINTA 745 was previously called AMG 745, which was originally being developed by Amgen.

Amgen and Atara
In October 2012, Amgen and Kleiner Perkins Caufield & Byers (KPCB) announced the formation of Atara Biotherapeutics, a new drug development company with a focus on innovative therapies for patients with chronic diseases in therapeutic areas including nephrology and oncology. Financial terms of the transaction are not being disclosed. Atara will have licenses to six Amgen assets, which are in various stages of development, ranging from preclinical to Phase I.


PINTA 745 News


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