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PneuGEM

Mucosis B.V.

Drug Names(s): PneuGEM

Description: PneuGEM is a Mimopath-based vaccine to prevent diseases caused by pneumococcal bacteria.

The Mucosis Mimopath technology stimulates the innate immune system through Toll-like receptor 2 (TLR2) to activate the adaptive immune system. The core of the Mimopath technology is the Bacterium-Like Particle (BLP). There are two modes of application of the BLPs. The first is an Add & Mix approach in which the immune stimulating properties of the BLPs are used to improve existing vaccines and to enable a mucosal route of administration. The second is a Bound approach in which the BLPs not only act as immunostimulant but also as a carrier for the subunit antigen(s). The binding of the antigens is achieved by a linker domain called Protan that binds to the surface of the BLPs.


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