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Drug Names(s): UCART123, engineered allogeneic T cells, CAR-T
Description: UCART123 is an allogeneic engineered T-cell product bearing a chimeric antigen receptor (CAR) targeting the CD123 antigen (also known as the interleukin-3 low affinity receptor).
Cellectis and MD Anderson
In September 2015, Cellectis and The University of Texas MD Anderson Cancer Center have entered into a research and development alliance aimed at bringing novel cellular immunotherapies to patients suffering from different types of liquid tumors. The alliance will build on MD Andersons translational and preclinical and clinical teams in leukemia and myeloma, coupled with Cellectis allogeneic CAR T-cell therapy approach and manufacturing capabilities, to pursue the development of Cellectis candidate products UCARTCS1, UCART22, UCART38 in T-cell ALL and UCART123 in a rare non curable disease BPDCN.
Partners: University of Texas MD Anderson Cancer Center
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