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Ubiquitin Specific Protease (USP) Program

Roche Holding AG

Drug Names(s): USP Program

Description: The Ubiquitin Specific Protease (USP) Program is a discovery and development program to identify small molecule inhibitors of a ubiquitin specific protease (USP) target.

Deal Structure: Genentech and Almac Discovery
In June 2015, Almac Discovery announced a Research and Licensing agreement with Genentech, a member of the Roche Group, to discover and develop small molecule inhibitors of a ubiquitin specific protease (USP) target. Under the terms of the agreement, Almac Discovery will receive an upfront payment of $14.5 million. Almac Discovery will be eligible to receive up to $349 million in payments based on achievement of certain predetermined milestones as well as escalating tiered royalties on potential commercial sales of multiple products to the target by Genentech. Almac Discoverys novel, potent and selective small molecule inhibitors will be the starting point for a two-year joint research program funded by Genentech. Genentech will be responsible for all preclinical and clinical development and commercialization of products arising from the collaboration.

Partners: Almac Group


Ubiquitin Specific Protease (USP) Program News


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