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Amphadase

Amphastar Pharmaceuticals, Inc.

Drug Names(s): bovine testicular hyaluronidase

Description: Amphadase is a preparation of purified bovine testicular hyaluronidase, a protein enzyme. Theexact chemical structure of this enzyme is unknown. However, the amino acid sequence forthe primary structure of the enzyme has been deduced from the sequence of purified peptides.

Hyaluronidase is being investigated for its ability to break down hyaluronic acid (HA), the space-filling gel-like substance that is a major component of tissues throughout the body. Hyaluronidase, injected in the skin or in the muscle, can temporarily digest the HA gel to enhance the penetration and diffusion of other injected drugs or fluids. When no spreading agent is present, subcutaneously injected materials tend to spread very slowly.


Amphadase News

Pink Sheet Approval In Brief


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