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CYC116

Cyclacel Pharmaceuticals, Inc.

Drug Names(s): CYC116

Description: CYC116 inhibits Aurora kinase (AK) and Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). Aurora kinases are enzymes that help dividing cells share their materials between two daughter cells. In many people with cancer, aurora kinase malfunctions and normal control of cell division is lost resulting in abnormal growth. Blocking VEGF receptors inhibits angiogenesis, the development of capillary blood vessels.


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