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177Lu-PSMA-SR6

Advanced Accelerator Applications SA

Drug Names(s): PSMA-SR6

Description: PSMA-SR6 is a second-generation selective prostate cancer Prostate-Specific Membrane Antigen (PSMA) receptor ligand. It's structure is selective for PSMA expressed on prostate cancer tumor cells.

Advanced Accelerator Applications plans to radiolabel PSMA-SR6 to develop a 177Lu-PSMA-SR6 to treat and monitor prostate cancer and a 68Ga-PSMA-SR6, which will help to diagnose and stage disease.

Deal Structure: Advanced Accelerator Applications and Johns Hopkins University
In January 2016, Advanced Accelerator Applications announced an exclusive license agreement with Johns Hopkins University to develop and market PSMA-SR6, a receptor ligand of Prostate-Specific Membrane Antigen (PSMA) for clinical therapeutic and diagnostic purposes. The terms of the agreement include payment to Johns Hopkins of an upfront licensing fee, as well as certain milestone and royalty payments.


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