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ALD Program

Biogen, Inc.

Drug Names(s): Adrenoleukodystrophy Program

Description: The ALD program is for the development of an adeno-associated virus (AAV)-based gene therapy platform for an undisclosed gene target.

Deal Structure: Biogen and Applied Genetic Technologies Corporation
In July 2015, Biogen and AGTC announced a broad collaboration and license agreement to develop gene-based therapies for multiple ophthalmic diseases. The lead development programs in the collaboration include a clinical candidate for X-linked Retinoschisis (XLRS) and a pre-clinical candidate for the treatment of X-Linked Retinitis Pigmentosa (XLRP).

Biogen will make an upfront payment in the amount of $124 million to AGTC, which includes a $30 million equity investment in AGTC at a price equal to $20.63 per share and certain prepaid research and development expenditures. Biogen will be granted a license to the XLRS and XLRP programs and the option to license discovery programs for three additional indications at the time of clinical candidate selection.

Under the collaboration, AGTC is eligible to receive upfront and milestone payments exceeding $1 billion. This includes up to $472.5 million collectively...See full deal structure in Biomedtracker

Partners: Applied Genetic Technologies Corporation

ALD Program News

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