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Takeda Pharmaceutical Company Ltd

Drug Names(s): VONOPION Pack, VONOPION (Takecab + Amolin + Fragile) [JP]

Description: VONOPION is a triple-drug blister pack containing TAKECAB, Amolin and Fragile tablet (generic name, metronidazole).

Deal Structure: Takeda and Otsuka
In March 2014, Otsuka and Takeda announced that the two firms have entered into a co-promotion agreement in Japan for TAK-438 (generic name: Vonoprazan Fumarate) for the treatment of acid-related diseases. The details of this agreement are as follows:

  • Otsuka will pay Takeda an up-front payment of 20 billion yen and a milestone payment upon NDA approval.
  • Otsuka will receive from Takeda a percentage of the sales (based on conditions specified in the contract).
  • Japan will be the area of promotion.
  • Further details will not be disclosed.

Partners: Otsuka Holdings Co., Ltd.


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