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Pfizer Inc.

Drug Names(s): Epirubicin hydrochloride

Description: Epirubicin is an anthracycline cytotoxic agent. Although it is known that anthracyclinescan interfere with a number of biochemical and biological functions within eukaryoticcells, the precise mechanisms of epirubicin’s cytotoxic and/or antiproliferative propertieshave not been completely elucidated.Epirubicin forms a complex with DNA by intercalation of itsplanar rings between nucleotide base pairs, with consequent inhibition of nucleic acid(DNA and RNA) and protein synthesis.

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