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FLAG Therapeutics, Inc.
Drug Names(s): FLAG003, FLAG 003, Flag Therapeutics-1, anti-angiogenic/anti-tubulin (AA/AT)
Description: FLAG-003 is a small anti-angiogenic/anti-tubulin (AA/AT) molecule, with both cytotoxic and cytostatic effects due to two distinct and well characterized mechanisms of action. It exhibits cytotoxic anti-tubulin activity through binding the colchicine site of tubulin causing microtubule depolymerization. It also exhibits anti-angiogenic activity through inhibiting RTK receptor tyrosine kinase (RTK) activity.
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