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Roche Holding AG

Drug Names(s): Nicardipine hydrochloride

Description: Cardene inhibits the transmembrane influx of calcium ions into cardiac muscle and smooth muscle without chaning serum calcium concentrations. The contractile process of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Cardene's effects apply more to vascular smooth muscle than cardiac muscle.

Deal Structure: All historical revenue for Cardene is recorded under Cardene IV.

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