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Emergent BioSolutions, Inc.
Description: ES425 is a bispecific immunotherapeutic protein that redirects T-cell cytotoxicity to tumor cells expressing ROR1 (receptor tyrosine kinase-like orphan receptor, an oncofetal antigen expressed on TNBC and other solid tumor and hematologic malignancies. ES425 was constructed using the ADAPTIR platform technology and will be further developed by Emergent’s planned spin-off company Aptevo Therapeutics.
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