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Drug Names(s): SDX7320, SDX 7320, fumagillol
Description: SDX-7320 is a methionine aminopeptidase 2 (MetAP2) inhibitor conjugated to a bio-compatible polymer which releases the pharmacologically active small molecule, fumagillol derivative, in vivo. The polymer conjugation approach reduces systemic drug exposure compared to the small molecule drug alone and keeps the active drug inert while in general circulation thereby reducing systemic toxicities.
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