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KPI-190

KPI Therapeutics, Inc.

Drug Names(s): Kv1.3 inhibitor

Description: KPI-190 is a topical, selective, Kv1.3 inhibitor peptide derived from the ShK family. Kv1.3 expressing, effector memory T cells (TEM cells) are present in conditions such as uveitis where they release cytokines and chemokines that lead to tissue damage in the eye. Targeting TEM lymphocytes without affecting naïve and central memory (TCM) lymphocytes, has the potential to effectively treat TEM-mediated diseases without inducing generalized immunosuppression.


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