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Ursodeoxycholic Acid

Retrophin, Inc.

Drug Names(s): Ursodeoxycholic Acid (Liquid Formulation)

Description: The original formulation from Retrophin is under the Cholbam profile.

Ursodeoxycholic acid is a naturally occurring hydrophilic bile acid derived from cholesterol.

Deal Structure: Retrophin and Asklepion
In June 2016, Retrophin announced the signing of a definitive agreement to purchase the rights, titles, and ownership of a liquid formulation of ursodeoxycholic acid from Asklepion Pharmaceuticals.

Under the terms of the agreement, Retrophin made an upfront payment of $0.5 million and will make future payments of up to $23.5 million based on cumulative sales milestones of liquid ursodeoxycholic acid in PBC. Asklepion will be eligible to receive incremental milestone payments of up to $35.0 million in aggregate upon successful development and commercialization, including cumulative sales milestones, of liquid ursodeoxycholic acid in additional indications. Retrophin will assume all future program costs and pay Asklepion tiered royalties on future product sales.

Partners: Asklepion Pharmaceuticals, LLC


Ursodeoxycholic Acid News


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