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SVP-Rapamycin/SVP-Insulin (Sanofi/Selecta)

Selecta Biosciences, Inc.

Drug Names(s): SVP-Rapamycin/SVP-Insulin

Description: Selecta is developing a gene therapy that combines SVP-Rapamycin (SEL-110) with SVP-insulin.

Deal Structure: Selecta and Sanofi
In October 2014, Selecta and JDRF extended their joint research collaboration and attracted Sanofi as a partner in support of their program to develop a Synthetic Vaccine Particle (SVP) immunotherapy with the long-term goal to treat and potentially prevent the underlying cause of type 1 diabetes. This collaborative research program is aimed at accelerating the advancement of an SVP immunotherapy designed to reset the immune system and restore tolerance to substances (antigens) that cause the immune attacks on insulin-producing cells in the pancreas.

As part of their collaboration, JDRF and Sanofi are co-financing the program with the aim of advancing the SVP product candidate to the clinic. This next phase of the SVP development program has been structured as a grant award to Selecta in order to test up to four antigens that may succeed in stopping the autoimmune response that destroys beta cells.

Partners: Sanofi

SVP-Rapamycin/SVP-Insulin (Sanofi/Selecta) News

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