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Amgen, Inc.

Drug Names(s): C326

Description: C326 is a novel protein therapeutic, designed to inhibit the function of interleukin-6 (IL-6), a pro-inflammatory cytokine that stimulates an immune response to trauma and has been shown to play a role in multiple disease indications. By inhibiting IL-6, C326 is designed to reduce or prevent symptoms associated with autoimmunity and inflammation. C326, as an Avimer drug candidate, has a unique structure that distinguishes it from antibodies, antibody fragments and other therapeutic proteins. Avimer proteins are much smaller than most therapeutic proteins and antibodies.

Deal Structure: In September 2006, Amgen entered into a definitive merger agreement to acquire Avidia. The transaction provided Amgen with C326.

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