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Merck & Co., Inc.
Drug Names(s): MK-0429
Description: MK-0429 is an alpha-V beta-3 integrin antagonist. Small-molecule, avß3 antagonists with a basic nitrogen separated some distance from a carboxylic acid to mimic RGD, a alpha-5, 8 and V ligand. avß3 Integrin, a cell/matrix attachment protein, which recognizes the amino acid motif Arg-Gly-Asp (RGD).
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