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Cumberland Pharmaceuticals Inc.
Drug Names(s): oral ifetroban
BioMedTracker has separate profiles for the injectable and oral formulations of ifetreoban. Please also see Hepatoren.
Portaban is an oral formulation of ifetroban. Ifetroban is a pharmacological antagonist of the thromboxane A2 / prostaglandin endoperoxide receptor (TPR). Ifetroban exhibits high-affinity for TPRs on platelets, vascular smooth muscle and certain other cell types and lacks agonistic activity. Ifetroban also displays anti-platelet and antivasospastic activities and is effective in certain preclinical models of vasospasm, thrombosis, reperfusion injury and endothelial dysfunction, including models that are insensitive to aspirin.
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