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Captisol-enabled Acetaminophen

Seelos Therapeutics, Inc.

Drug Names(s): Captisol-enabled Acetaminophen

Description: Seelos is developing a licensed Captisol-enabled acetaminophen program for pain and fever management.Captisol is a patent-protected, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.

Deal Structure: Ligand and Seelos
In September 2016, Ligand Pharmaceuticals announced the licensing of rights to four programs to Seelos Therapeutics.The licensed therapeutic programs include Ligand's aplindore (now known as SLS-006) program for the treatment of various CNS disorders, a CRTH2 antagonist program for the treatment of respiratory disorders, a Captisol-enabled acetaminophen program for pain and fever management and an H3 receptor antagonist program for the treatment of narcolepsy.

Under the license agreement, Ligand is entitled to receive initial payments in equity or cash of $1.3 million upon Seelos completing a minimum of $7.5 million financing and up to an additional $3.5 million if Seelos becomes a public company and up to $145 million of additional cash milestones. In addition, Ligand is entitled to net sales royalties ranging from 4% to 10% for the various programs licensed. Ligand has also entered into a supply agreement for Captisol. If certain conditions are...See full deal structure in Biomedtracker

Partners: Ligand Pharmaceuticals, Inc.

Captisol-enabled Acetaminophen News

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