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ACEA Biosciences Inc.
Drug Names(s): AC 0010MA, AC0010, AC 0010
Description: AC0010MA is an orally available selective inhibitor of mutant forms of the epidermal growth factor receptor (EGFR), including the second-site resistance mutation T790M, with potential antineoplastic activity for the treatment of non-small cell lung cancer. AC0010MA specifically and irreversibly binds to and inhibits the activity of mutant forms of EGFR, preventing EGFR mutant-mediated signaling and leads to cell death in EGFR mutant-expressing tumor cells.
Pink Sheet Chart: FDA Recalls -- Aug. 25, 2010
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