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Ono-Merus Bispecific Antibody

Ono Pharmaceutical Company, Ltd.

Drug Names(s): Merus-Ono Bispecific Antibody

Description: Merus and Ono are co-developing an autoimmune bispecific antibody, utilizing Merus' bispecific antibodies, Biclonics, that have a full-length IgG format.

Deal Structure: Merus and Ono
In April 2014, Merus and Ono executed a research and license agreement to jointly develop bispecific antibody therapies in autoimmune diseases. In April 2015, Merus received a milestone payment for achieving preclinical proof-of-concept with a lead bispecific antibody. In October 2016, Merus announced that Ono and Merus have also extended their collaboration by signing an additional agreement for CMC activities to be carried out by Merus.

Partners: Merus B.V.

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