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Drug Names(s): ABT-894, sofinicline
Description: ABT-894 is a neuronal nicotinic acetylcholine receptor (NNR) modulator targeting the alpha4beta2 NNR receptor. In preclinical models, ABT-894 demonstrated a pain-relieving effect in line with that of morphine but without the adverse effects normally associated with morphine and other similar drugs.
Deal Structure: ABT-894 was selected as the first development candidate under a research, development and license agreement with NeuroSearch A/S covering Neuronal Nicotinic Receptor (NNR) modulators. Abbott is responsible for the clinical development and commercialisation of ABT-894 and will under the terms of the agreement finance all development costs and pay milestones and royalties to NeuroSearch.
Partners: NeuroSearch A/S
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