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Pomalyst

Celgene Corporation

Drug Names(s): CC-4047, Actimid, pomalidomide, Imnovid (EU)

Description: Actimid is a member of a new class of novel immunomodulatory drugs, or IMiDs, which are chemically similar to thalidomide. Like thalidomide, actimid affects the immune system in multiple ways including the inhibition of angiogenesis and inflammatory cytokine production.

Another major target may be the ligase protein, cereblon (CRBN; http://www.nature.com/leu/journal/v26/n11/full/leu2012119a.html).


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