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Sermonix Pharmaceuticals LLC

Drug Names(s): Oporia, Lasofoxifene, CP336 156

Description: Oporia (Lasofoxifene) is a second-generation non-steroidal estrogen partial agonist. It belongs to the selective estrogen receptor modulators (SERMs) family of drugs.

Deal Structure: Ligand and Pfizer
In 1991, Ligand Pharmaceuticals entered into a research and development collaboration with Pfizer to develop therapies for osteoporosis.

Under the terms of the agreement between Ligand and Pfizer, Ligand is entitled to receive an additional milestone upon the first FDA approval of Oporia (lasofoxifene) and, if marketed, royalty payments equal to 6% of net sales of lasofoxifene worldwide for any indication.

In July 2011, Ligand executed a patent license agreement for the exclusive license, under the Licensed Patents, to make, have made, import, use, sell or offer for sale the compound associated with Fablyn. The licenses and rights granted are free of any ongoing obligations to Pfizer.

Ligand and Royalty Pharma
In March 2002, Ligand announced an agreement with Royalty Pharma AG, which purchased rights to a share of future payments from Ligand's collaborative partners' sales of three SERM products (lasofoxifene, bazedoxifene, and...See full deal structure in Biomedtracker

Partners: Royalty Pharma AG Azure Biotech, Inc. Ethicor Pharma Ltd. Ligand Pharmaceuticals, Inc.

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