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Trek Therapeutics, PBC

Drug Names(s): VX-497, MMPD

Description: Merimepodib targets hepatitis C indirectly through the inhibition of inosine monophosphate dehydrogenase.

Deal Structure: Vertex and Trek Therapeutics
In July 2016, Trek Therapeutics announced that it acquired the worldwide development and commercialization rights to treat infectious disease with lomibuvir (VX-222), a non-nucleoside inhibitor of the HCV NS5B polymerase and merimepodib (VX-497), an inhibitor of inosine monosphosphate dehydrogenase with broad-spectrum antiviral properties from Vertex Pharmaceuticals.

Vertex will be eligible to receive milestones and royalties based on successful development and commercialization of lomibuvir and merimepodib. Other terms were not disclosed.

Partners: Vertex Pharmaceuticals Incorporated

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