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MDX-214

Bristol-Myers Squibb Company

Drug Names(s): Anti-EGFr/CD89 Antibody

Description: MDX-214 is believed to target the epidermal growth factor receptor (EGFr). Preclinical in vitro studies suggest that MDX-214 may provide an unusually potent approach to treating EGFr-positive cancers by inhibiting tumor cell growth and by mediating antibody-dependent cellular cytotoxicity (ADCC).

Deal Structure: MDX-214 was originally developed by Medarex.

In July 2009, Bristol-Myers Squibb and Medarex announced that the companies signed a definitive merger agreement providing for the acquisition of Medarex by Bristol-Myers Squibb, for $16.00 per share in cash. The acquisition was closed in September 2009.


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