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AstraZeneca PLC

Drug Names(s): lerdelimumab, CAT-152

Description: Trabio is a human anti-TGFß2 monoclonalantibody in development as an anti-scarring agent,particularly following eye surgery. TGFß2hyperactivity is associated with post-operativescarring in and around the eye. Post-operativescarring is the major reason for long-termophthalmologic surgical failure in these clinicalscenarios.

Deal Structure: Trabio was developed by Cambridge Antibody Technology (CAT). In June 2006, CAT became a subsidiary of AstraZeneca.

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