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Drug Names(s): CyIS, Aerosolized Cyclosporine
Description: PULMINIQ is an inhaled formulation of cyclosporine, an FDA-approved drug that has been part of the standard of care for heart, kidney and liver transplant patients for more than 20 years. Cyclosporine is a powerful immunosuppressant that has had a significant impact on transplant medicine. It inactivates T cells by inhibiting calcineurin phosphatase activity resulting in the inhibition of the transcription factor nuclear factor of activated T cells (NFAT).
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