This web site is part of the Business Intelligence Division of Informa PLC
This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.
Johnson & Johnson
Drug Names(s): oxybutynin chloride
Description: Ditropan (Oxybutynin chloride) is an antispasmodic, anticholinergic agent. Oxybutynin has a dual mechanism of action. Contraction of the smooth muscle of the bladder is stimulated by the release of acetylcholine by the nerves within the bladder and the attachment of the acetylcholine to receptors on the surface of the muscle cells. Oxybutynin suppresses involuntary contractions of the bladder's smooth muscle (spasms) by competitively blocking the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor (M1 may play a role in acetylcholine release). Oxybutynin also directly relaxes the bladder's outer layer of muscle (the detrusor muscle) as a calcium antagonist, though this is thought to occur at higher concentrations.
Pink Sheet Alza Ditropan XL
Additional information available to subscribers only: