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Johnson & Johnson

Drug Names(s): oxybutynin chloride

Description: Ditropan (Oxybutynin chloride) is an antispasmodic, anticholinergic agent. Oxybutynin has a dual mechanism of action. Contraction of the smooth muscle of the bladder is stimulated by the release of acetylcholine by the nerves within the bladder and the attachment of the acetylcholine to receptors on the surface of the muscle cells. Oxybutynin suppresses involuntary contractions of the bladder's smooth muscle (spasms) by competitively blocking the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor (M1 may play a role in acetylcholine release). Oxybutynin also directly relaxes the bladder's outer layer of muscle (the detrusor muscle) as a calcium antagonist, though this is thought to occur at higher concentrations.

Ditropan News

Pink Sheet Alza Ditropan XL

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