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ZIOPHARM Oncology, Inc.

Drug Names(s): ZIO-301, Indibulin

Description: ZIO-301 is a novel anti-cancer agent that binds to tubulin, one of the essential proteins for chromosomal segregation, and targets mitosis like the taxanes and Vinca alkaloids. ZIO-301 binds to a site on tubulin that is different from the taxanes or Vinca alkaloid binding sites. In contrast to taxanes, which stabilize tubulin polymers, indibulin destabilizes tubulin polymerization.

Deal Structure: Indibulin was acquired from Baxter Healthcare.

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