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Drug Names(s): SSR149415

Description: SSR149415 is a selective and orally active non-peptide antagonist of vasopressin V(1b) receptors. Through pituitary and central vasopressin V1b receptors, vasopressin participates in the control of the hypothalamic-pituitary-adrenal axis (HPA) and is involved in various emotional processes. SSR149415 potently antagonizes functional cellular events associated with V1b receptor activation by vasopressin, such as intracellular Ca2+ increase or proliferation in various cellsystems.

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