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Rucaparib

Clovis Oncology, Inc.

Drug Names(s): PF-1367338, PF-01367338, AG-14699, AG14699, CO-338

Description: Rucaparib is an oral, small molecule inhibitor of poly ADP-ribose polymerase 1 (PARP1), PARP2 and PARP3

Deal Structure: AG-14,699 was developed by Agouron Pharmaceuticals.

Warner-Lambert and Agouron
In May 1999, Warner-Lambert acquired Agouron Pharmaceuticals (Agouron).

Pfizer and Warner-Lambert
In June 2000, Pfizer completed its merger with Warner-Lambert.

Clovis and Pfizer
In June 2011, Clovis announced an agreement with Pfizer for the development and commercialization of PF-01367338.

Under the terms of the agreement, Clovis will take over responsibility for global product development and commercialization. Pfizer will receive an upfront license fee from Clovis, payable in equity in Clovis, and will be eligible to receive further payments totaling up to $255 million upon Clovis' successful attainment of development, regulatory and sales milestones. Pfizer will also receive royalties on any product sales. In addition, Pfizer will make a separate equity investment in Clovis Oncology.

Clovis and AstraZeneca
In April 2012, Clovis entered into a...See full deal structure in Biomedtracker

Partners: Pfizer Inc.


Rucaparib News


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