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Astellas Pharma, Inc.

Drug Names(s): darexaban maleate

Description: YM150 is an oral Factor Xa inhibitor. Factor Xa is an enzyme that leads to blood clot formation by converting prothrombin to thrombin. The antithrombotic agent is being developed for two applications, prevention of venous thromboembolism (VTE) after orthopedic surgery and prevention of thromboembolism accompanying atrial fibrillation (AF).

Deal Structure: In April 2005, Yamanouchi and Fujisawa merged to form Astellas Pharma.

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