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Equetro

Validus Pharmaceuticals

Drug Names(s): Bipotrol, Carbamazepine Extended Release, SPD417, ERC-CBZ

Description: Equetro is a twice daily formulation of carbamazepine. The mechanisms of action of carbamazepine in the treatment of bipolar disorder has not been elucidated. Although numerous pharmacological effects of carbamazepine have been described (e.g., modulation of ion channels [sodium and calcium], receptor-mediated neurotransmission[GABAergic, glutamatergic, and monoaminergic], and intracellular signaling pathways), the contribution of these effects to the efficacy of carbamazepine in bipolar disorder is unknown.

Deal Structure: In September 2007, Validus Pharmaceuticals announced that it had acquired Equetro (carbamazepine) extended release capsules, from Shire plc.


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