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Roche Holding AG

Drug Names(s): R1511

Description: R1511 is a glucokinase activator. Glucokinase attaches a phosporous group to glucose. The enzyme regulates carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to rising or falling levels of glucose. In the liver, it facilitates the uptake and metabolism of glucose. In the pancreas, it appears to be involved in the regulation of insulin secretion.

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