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Exforge HCT Combo

Novartis AG

Drug Names(s): Diovan/Exforge/Valsartan/Imprida/Dafiro/Copalia + amlodipine + hydrochlorothiazide (HCT), Dafiro HCT

Description: Valsartan/amlodipine/hydrochlorothiazide is a combination of the angiotensin II receptor antagonist valsartan (Diovan), the calcium channel blocker amlodipine, and the diuretic hydrochlorothiazide. Valsartan inhibits the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Aldosterone acts on the kidneys to increase retention of sodium and fluid, and on the central nervous system to increase thirst. Amlodipine dilate blood vessels. Hydrochlorothiazide also acts on the kidneys to reduce resorption of sodium and fluid.

Deal Structure: Exforge HCT was originally developed by Novartis.

In August 2009, UCB and Novartis announced that they entered into a licensing agreement for cardiovascular and diabetes products in Germany. Under the agreement, UCB licensed in commercial rights for Dafiro (valsartan and amlodipine) and Dafiro HCT (valsartan, amlodipine and HCT).

Partners: UCB SA

Exforge HCT Combo News

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