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GSK 239512

GlaxoSmithKline plc

Drug Names(s): GSK239512

Description: GSK 239512 is a histamine H3 antagonist. Histamine H3 receptors are expressed in the central nervous system and, to a lesser extent, the peripheral nervous system. They are located presynaptically on nerve cells and their activation inhibits the release of histamine and other neurotransmitters (depending on the nerve cell), such as GABA, acetylcholine, noradrenaline, and serotonin. They have been implicated in cognition, as well as other functions.


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