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Drug Names(s): XP21279
Description: XP21279 is a new chemical entity that is a Transported Prodrug of L-Dopa. XP21279 is designed to engage natural nutrient transport mechanisms located throughout the length of the gastrointestinal, or GI, tract, and then be rapidly converted to L-Dopa by the body's endogenous enzymes. In addition to L-Dopa, the metabolic breakdown products of XP21279 are substances with favorable safety characteristics. Because XP21279 is designed to be well absorbed from the lower GI tract, it may be formulated for sustained release, thus reducing fluctuations of L-Dopa levels in the bloodstream.
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